The LDS church interprets Romans 9:18-21 as teaching God's sovereign choice and predestination according to his foreknowledge. This supports the LDS doctrine that God foresaw who would accept the Gospel and organized the plan of salvation accordingly.

LDS theology teaches that God's election is based on foreknowledge and divine purposes. This is compatible with LDS belief in the pre-mortal existence: in the pre-mortal realm, spirits made choices that influenced their earthly roles and blessings. God's sovereignty and human choice are both real in LDS understanding. The passage supports the doctrine that God knows all things and directs his church according to his eternal purposes, which is central to LDS claims about continuing revelation and modern apostolic leadership.