The Maronite Catholic Church affirms that Isaiah 7:14 is a messianic prophecy of the virgin birth of Christ, fulfilled in Mary the mother of Jesus. The Maronite liturgical tradition honors Mary as Theotokos (Mother of God) and celebrates her perpetual virginity (before, during, and after Christ's birth), consistent with Eastern Catholic tradition and Catholic dogma. The Fourth Lateran Council and the Council of Trent affirmed the virgin birth as a doctrine of the Catholic faith.

In Maronite theology and spirituality, the virgin birth is inseparable from Marian devotion and the incarnational mystery. Isaiah's prophecy is understood as a direct and literal fulfillment in the person of Mary. The Maronite Synod (1736) reaffirmed traditional Catholic teaching on Mary's perpetual virginity.