Iglesia ni Cristo affirms that Jesus Christ will return to judge all humanity. At his second coming, Christ will judge the living and the dead, separating the righteous from the wicked. INC members who have remained faithful will be saved and inherit eternal life, while those outside the Church will face eternal destruction. The second coming is understood as the culmination of history and the final vindication of INC's teaching and leadership.

The timing of the second coming is not specified with certainty, but the doctrine is affirmed as essential to Christian faith. The return of Christ is understood as the ultimate enforcement of God's justice and the fulfillment of his purposes in history. For INC members, the hope of Christ's return provides motivation for continued faithfulness and obedience to the Church. The second coming is presented as the final and irreversible separation of the saved (INC members) from the lost (all others).