The Syro-Malabar Church affirms a sacramental priesthood distinct from the general priesthood of all believers. Ordained priests are understood to possess special grace and authority to offer the sacrifice of the Mass (the Eucharist) and to administer the sacraments. Ordination is one of the seven sacraments and effects an indelible mark on the soul (character).

The ordained ministry in the Syro-Malabar Church includes deacons, priests, and bishops. Deacons are ordained to assist in the service of the church, particularly in the administration of the sacraments and the care of the poor. Deacons in the Syro-Malabar Church may be married, as is the tradition in Eastern Christianity. Priests, who may also be married (following Eastern Christian practice unlike the Latin Church), preside over parishes and offer the Eucharist.

Bishops are understood as successors of the apostles and possess the fullness of apostolic authority. Only bishops can ordain new clergy and are understood to be the guardians of the faith in their dioceses. While the Syro-Malabar Church permits a married clergy (a significant distinction from the Latin Church's celibate priesthood), entrance into monasticism and the acceptance of celibacy is honored as a higher calling.