Christadelphians hold a nuanced position on Revelation 20:1-6, with some variation in interpretation. Generally, the Church expects a literal or semi-literal millennial kingdom on earth following Christ's return. This is consistent with Christadelphian literalistic hermeneutics and emphasis on biblical prophecy. The thousand-year period is often understood as the time of Christ's reign on earth before the final judgment and the age to come.

Christadelphian eschatology emphasizes the bodily resurrection of believers and the establishment of God's kingdom on earth, in continuity with Old Testament prophecies of restoration and peace. Revelation 20:1-6 is understood within this framework as describing the millennium as a real historical event following Christ's parousia. The first resurrection may be understood as spiritual (the resurrection of the just at Christ's return) or as including literal bodily resurrection.