Seventh-day Adventism affirms the traditional reading of Isaiah 7:14 as a Messianic prophecy fulfilled in Jesus's virgin birth. The passage announces that a virgin (עַלְמָה) will conceive and bear a son named Immanuel. This prophecy is understood as a sign of God's redemptive plan, with the Messiah entering human history through the miraculous virgin conception.

Adventist theology emphasizes that the virgin birth establishes Christ's sinless nature and humanity. Ellen G. White affirmed the virgin birth, and the 28 Fundamental Beliefs (Belief 4) affirm Christ's incarnation through Mary. This miraculous birth points to the reality of God's intervention in human history and the beginning of Christ's redemptive mission.