Jehovah's Witnesses reject the traditional Christian interpretation of Isaiah 7:14 as predicting a virgin birth. The Hebrew word 'almah' means 'young woman' rather than 'virgin,' and the prophecy originally referred to a sign in Isaiah's own time, not to a future Messiah. Jesus was born of a virgin (Mary) through God's act, but this was not prophesied in Isaiah 7:14.

For Witnesses, Jesus is the Son of God, uniquely born of God, but not eternally divine. The virgin birth is affirmed as a fact but not as the fulfillment of Isaiah 7:14. This interpretation is part of Witnesses' distinctive Christology that emphasizes Jesus as God's firstborn creation rather than as God the Son in an eternal Trinity.