Independent Fundamental Churches affirm Isaiah 7:14 as a clear, direct messianic prophecy of the virgin birth of Jesus Christ. This interpretation is standard in fundamentalist and evangelical Protestantism and is based on the word 'almah' (virgin in the traditional rendering) and the apostolic interpretation in Matthew 1:22-23.

The virgin birth of Christ is a cardinal doctrine for Independent Fundamental churches, attesting to Christ's sinless nature, his divine origin, and God's supernatural intervention.