The Coptic Orthodox Church includes Mark 16:9–20 within its biblical canon and affirms it as part of the apostolic tradition. The Coptic Orthodox received this text through the Alexandrian manuscript tradition and its liturgical practice, which has preserved the full longer ending as authentic Scripture. The passage is read in Coptic Orthodox churches and cited in the traditional commentary on Mark, reflecting the Church's commitment to the patristic reception of the biblical text.

For the Coptic Orthodox, textual criticism is approached through the lens of patristic and liturgical tradition. While modern scholarship notes the absence of this ending in certain early manuscripts, the Coptic Orthodox Church—whose textual tradition reflects the Alexandrian recension—maintains its inclusion as authoritative. The post-resurrection appearances of Christ and the commission to the disciples recorded in Mark 16:9–20 are integral to Coptic Orthodox Christology and pneumatology. The Church's long liturgical use of this passage substantiates its canonical authority within Coptic Orthodoxy.