Churches of Christ affirm the full inspiration and authority of Scripture. The Bible is the Word of God written through human authors by divine inspiration and is without error in all that it affirms. This conviction is the practical foundation of the Restoration principle: if Scripture is not fully reliable, the movement's commitment to return to its pattern collapses.

Churches of Christ approach Scripture with a high level of confidence in its reliability, typically holding to something equivalent to what evangelicals call inerrancy, though the specific terminology varies by teacher. Historical-critical approaches that undermine Scripture's authority are generally rejected. The hermeneutical approach tends toward a plain, grammatical-historical reading of the text.