The Brethren in Christ affirm salvation by God's grace through faith in Christ, with strong emphasis on new birth (regeneration) and progressive sanctification. This reflects Wesleyan-Arminian theology: salvation is a gift, but human response in faith is necessary. Prevenient grace enables the human will to respond to God's call.

Entire sanctification is taught as a second work of grace, distinct from justification. Believers are invited to present themselves wholly to God, seeking cleansing from indwelling sin and consecration to God's service. This is not portrayed as automatic but as an invitation requiring faith and the work of the Holy Spirit.

Critically, the Brethren in Christ do not teach the doctrine of eternal security. A person genuinely saved can fall away through willful rejection of grace. Believer's baptism and continued discipleship are signs of salvation's reality, but the church recognizes the possibility of apostasy.