Biblical Unitarians generally stand within the Arminian tradition on predestination: God foreknew who would respond to the gospel in faith, but this foreknowledge does not predetermine or coerce human choice. Salvation is genuinely offered to all, and individuals are genuinely free to accept or reject it. Calvinist unconditional election is typically rejected as incompatible with both divine justice and the genuine universality of the gospel offer.

The movement's broadly Arminian orientation is consistent with its emphasis on personal moral responsibility and its rejection of original sin in the Augustinian sense. If humans have genuine moral freedom and are not born under irresistible inherited guilt, then it is coherent that their response to the gospel is genuinely free and that God's election is based on foreknown faith rather than unconditional decree.

Some Biblical Unitarians hold an open theism perspective — the view that God's foreknowledge of free human choices is not exhaustive, so that the future remains genuinely open and God responds to human decisions in real time. This further emphasizes genuine creaturely freedom over against any form of divine determinism. The Biblical Unitarian movement is not monolithic on this point, but the direction is consistently away from Calvinist predestinarianism.